There has never been a better time to discuss the immune building power of omega-3 fatty acids. Usually, you hear us discuss these essential micronutrients in term of how they help build bone, and fight inflammation. But, did you know they also boost the immune response. That’s right! Omega 3 fatty acids like those found in fish oil can help your body fight off unfriendly foes. Let’s learn more.

In an October 2019 review in the International Journal of Molecular Sciences, the authors reviewed research on the clinical applications of omega-3 fatty acids for immune disorders in detail and confirmed the importance of the role of omega-3, specifically EPA and DHA, in the functioning of the immune system. The review considers the effects these omega-3 fatty acids on many immune cells including: macrophages, cytokines, neutrophil function, T cells (including T regulatory cells), B cells, dendritic cells, natural killer cells, mast cells, basophils and eosinophils.

The understanding that omega-3s are a constitutive part of the cellular membranes is not new information. For example we know they help to regulate cellular membrane properties such as membrane fluidity and complex assembly in lipid rafts. However, more recently a new role for omega-3 fatty acids and their derivatives as signaling molecules has emerged. It is thought that this could be due to disruption of pro-inflammatory cascades, by altering cell signaling, cytokines and pro-inflammatory mediators.

Interestingly, some specific immune functions are promoted by dietary omega-3 fatty acids in specific immune cell types, e.g. phagocytosis by macrophages and neutrophils or T-reg differentiation, suggesting that omega-3 fatty acids do not act as unspecific immune-repressors.

Together, this means that maintaining omega-3 saturation is a year-round priority to ensure that optimal immune function is achieved.

Additionally, a study, published in the Journal of Leukocyte Biology​​, suggests that instead of suppressing the immune system by reducing inflammation, consumption of DHA and EPA-rich fish oil may actually enhance the function of immune B cells. The primary responsibility of B-cells involves the body's response to foreign invaders through what is known as humoral immunity. They play a major role in the immune system, which guards the body against infection.

As you can see, a quality omega 3 supplement containing clinical quantities of EPA and DHA may be another important tool when trying to boost your immune system, both by lowering inflammation and by directly acting to increase immune strength.


We formulated Origin Omega to be the highest quality, triglyceride form, triple strength fish oil product on the market. Our patented anti-competition technology separates the clinical quantities of EPA and DHA into AM and PM doses for increased absorption and utilization. You can learn all about our Origin Omega, and how to identify a high quality omega-3 supplement by downloading our free guide to the omegas here.

Stay safe and well,

Mira & Jayson